Spondyloarthritis & psoriatic arthritis

An app-based nonpharmacological intervention improves patient-reported disease activity, functionality, and quality of life in patients with axial spondyloarthritis: a randomised controlled trial

Ann Rheum DisPublished Randomised controlled trial

Primary result · BASDAIResult — go to the resultANCOVA-estimated group difference −1.508

Authors' conclusion

These findings support the potential of Axia as a safe and effective nonpharmacological intervention to further improve the state of care of patients with axSpA in addition to conventional anti-inflammatory pharmacotherapy.

Study context

Population
Patients with axial spondyloarthritis (axSpA) on stable pharmacotherapy186 completed
Participants
200 patients
Comparison
Axia smartphone app vs standard of care
Primary endpoint
BASDAI
Follow-up
12 weeks
Methodological detailsmonocentric, 1:1 randomisation, 12-week
  • Monocentric
  • 1:1 randomisation
  • 12-week

Primary result

As reported in the abstract

ANCOVA-estimated group difference

−1.508

P < 0.001

Further findings

ASAS20 response · 12 weeks

P < 0.001

ASAS40 response · 12 weeks

P < 0.001

OutcomeANCOVA-estimated group differenceP value
BASFI · 12 weeksExceeding MCID threshold−1.139P < 0.001
ASQoL questionnaire · 12 weeksExceeding MCID threshold−2.297P < 0.001

Original publication

An app-based nonpharmacological intervention improves patient-reported disease activity, functionality, and quality of life in patients with axial spondyloarthritis: a randomised controlled trial. Ann Rheum Dis. Published 13 March 2026. doi:10.1016/j.ard.2026.02.016

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