Spondyloarthritis & psoriatic arthritis

One-year effectiveness of long-term exercise therapy in people with axial spondyloarthritis and severe functional limitations

Rheumatology (Oxford)Published Randomised controlled trial

Primary result · Change in PSC1 (0-10)Result — go to the resultMean difference −1.8 95% CI −2.4 to −1.2

Authors' conclusion

Long-term, supervised exercise therapy proved more effective than usual care in improving functional disability and physical quality of life in people with axSpA and severe functional limitations.

Study context

Population
People with axial spondyloarthritis (axSpA) and severe functional limitations49% female, age 52 (SD 12) years
Participants
214 people
Comparison
Long-term personalised supervised exercise therapy vs usual care
  • Interventionn = 110
  • Usual caren = 104reference
Primary endpoint
Change in Patient-Specific Complaints activity ranked 1 (PSC1, 0-10)
Follow-up
52 weeks
Methodological details1:1 randomisation, supervised exercise therapy vs usual care
  • 1:1 randomisation
  • Supervised exercise therapy vs usual care

Primary result

Change in PSC1 (0-10)

Mean difference

−1.8

95% CI −2.4 to −1.2

Interventionvs Usual care
mean difference −1.8 (95% CI −2.4 to −1.2)

As reported in the abstract

Secondary outcomes

Treatment uptake in intervention
40.5 · mean · SD 15.1 · sessions

Secondary outcomes (PSC2, PSC3, BASFI, 6-min walk test, PROMIS-PF-10, SF-36 PCS) · 52 weeks

All secondary outcomes except SF-36 MCS significantly greater improvement with intervention; effect sizes
0.4 to 0.7

Original publication

One-year effectiveness of long-term exercise therapy in people with axial spondyloarthritis and severe functional limitations. Rheumatology (Oxford). Published 8 June 2024. doi:10.1093/rheumatology/keae323

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