Spondyloarthritis & psoriatic arthritis
Evaluation of pregnancy outcomes in patients with spondyloarthritis compared to the general population: results from a French national prospective and matched study
Main finding · SGA (the most common adverse pregnancy outcome)Result — go to the resultOdds ratio 1.94 95% CI 1.09–3.39Authors' conclusion
In this contemporary cohort, compared to the general population, SpA was associated with a higher risk of SGA, but no other adverse pregnancy outcomes, providing reassurance for most pregnant women with SpA.
Study context
- Population
- Pregnant women with spondyloarthritis (SpA), France, December 2015 to June 2021 (mean age 32.1 years; mean disease duration 6.3 years; 50.4% nulliparous)SpA pregnancies in 124 women
- Participants
- 135 SpA pregnancies
- Exposure
- SpA pregnancies vs matched general population women
- Outcome
- Frequency of adverse pregnancy outcomes
Methodological detailsmulticentre, matched (1:4) general population controls, logistic regression
- Multicentre
- Matched (1:4) general population controls
- Logistic regression
Main finding
SGA (the most common adverse pregnancy outcome)
Odds ratio
1.94
95% CI 1.09–3.39
By group
SpAvs Controls
OR 1.94 (95% CI 1.09–3.39)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Predictors of small for gestational age (SGA) in women with SpA
- No predictor of SGA identified
Original publication
Evaluation of pregnancy outcomes in patients with spondyloarthritis compared to the general population: results from a French national prospective and matched study. Ann Rheum Dis. Published 15 November 2025. doi:10.
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