Spondyloarthritis & psoriatic arthritis
Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis
Authors' conclusion
In this systematic review, US enthesitis was highly prevalent in PsA patients. Evidencing enthesitis by US was found to be reasonably specific and could contribute to the diagnosis of PsA; power Doppler was highly specific, however it was rarely present.
Study context
- Population
- Adult patients with confirmed PsA, with or without non-PsA controls; PubMed 2010 to June 202376 articles
- Comparison
- US enthesitis in PsA vs non-PsA controls
- PsAn = 5,927
- Controlsn = 3,423reference
- Outcome
- Specificity of US enthesitis (Mode B and power Doppler) for PsA diagnosis
Methodological detailsunivariate random effects meta-analysis
- Univariate random effects meta-analysis
Pooled result
As reported in the abstract
Pooled diagnostic performance of US enthesitis for PsA
| Group | Sensitivity | Specificity |
|---|---|---|
| Mode B US | 62.1% (47.9-76.4%)Sensitivity on a scale from 0 to 100 percent | 73.2% (59.3-87.0%)Specificity on a scale from 0 to 100 percent |
| Power Doppler | 14.7% (8.2-21.2%)Sensitivity on a scale from 0 to 100 percent | 97.9% (96.5-99.5%)Specificity on a scale from 0 to 100 percent |
Sensitivity
Mode B US62.1% (47.9-76.4%)
Power Doppler14.7% (8.2-21.2%)
Sensitivity on a scale from 0 to 100 percentSpecificity
Mode B US73.2% (59.3-87.0%)
Power Doppler97.9% (96.5-99.5%)
Specificity on a scale from 0 to 100 percentFurther pooled results
| Outcome | PsA | Controls |
|---|---|---|
| Prevalence of US enthesitis (≥1 enthesitis) | 73.7% (95% CI 56.6–90.9%) | 12.6% (95% CI 2.6–22.3%) |
Most specific enthesitis site
- Achilles tendon most frequently involved in PsA but not in controls; erosions and power Doppler activity most discriminant
Original publication
Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis. Rheumatology (Oxford). Published 20 December 2024. doi:10.
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