Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis
Authors' conclusion
Two years after the PFJ intervention, improvements in RA disease activity, MSOA symptoms and functioning, and intervention adherence were sustained.
Study context
- Population
- People with rheumatoid arthritis (RA) or metabolic syndrome-associated hip or knee OA after the Plants for Joints intervention (whole-food plant-based diet, exercise, stress reduction)48 RA and 44 MSOA completed
- Participants
- 77 vs 64
- Comparison
- Two years after the Plants for Joints (PFJ) intervention vs start and end of intervention
- RAn = 77
- MSOAn = 64
- Primary endpoint
- DAS28 (RA) and WOMAC (MSOA)
- Follow-up
- Two years after intervention
Methodological detailstwo-year follow-up, linear mixed models, within-group comparisons
- Two-year follow-up
- Linear mixed models
- Within-group comparisons
Primary result
As reported in the abstract
Within-group change vs start intervention
Estimate (95% CI)
RA
DAS28 change vs start intervention −0.9 points(−1.2 to −0.6)
MSOA
WOMAC change vs start intervention −8.8 points(−12.6 to −5.1)
Secondary outcomes
Secondary outcomes vs start intervention · two years after intervention
- CRP significantly lower in RA
- Weight, BMI, waist circumference and diastolic blood pressure significantly lower in MSOA
- Medication use decreased slightly; participants continued to follow intervention recommendations
Original publication
Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis. Arthritis Care Res (Hoboken). Published 20 April 2025. doi:10. 1002/ acr. 25553
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