Lupus & antiphospholipid syndrome

Towards an understanding of the biopsychosocial determinants of cardiovascular disease (CVD) in systemic lupus erythematosus (SLE): a scoping review

Lupus Sci MedPublished Scoping review

Authors' conclusion

While several social factors contribute to CVD in SLE populations, considerable gaps remain as many social determinants remain un(der)explored.

Study context

Population
Studies of social factors influencing the development of CVD in SLE9 studies included
Participants
9 participants
Outcome
Social factors influencing the development of CVD in SLE
Methodological detailsPRISMA extension for Scoping reviews, four databases (PubMed, SCOPUS, PsychINFO, CINAHL), 682 studies identified for screening; screened in two phases (title/abstract and full text)
  • PRISMA extension for Scoping reviews
  • Four databases (PubMed, SCOPUS, PsychINFO, CINAHL)
  • 682 studies identified for screening; screened in two phases (title/abstract and full text)

Main finding

As reported in the abstract

Themes of social factors (studies, n)
Socioeconomic status and education
n=5; 56%
Race and/or ethnicity
n=7; 78%
Mental health
n=2; 22%
Gender
n=3; 33%
Healthcare quality and/or insurance
n=2; 22%

Further findings

Characteristics of included studies

Cross-sectional
Six studies (67%)
Longitudinal
three (33%)
SLE cohorts
n=7, 78%
Healthcare databases
n=2; 22%
All conducted in the USA between 2009 and 2017

Original publication

Towards an understanding of the biopsychosocial determinants of CVD in SLE: a scoping review. Lupus Sci Med. Published 24 July 2024. doi:10.1136/lupus-2024-001155

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