Spondyloarthritis & psoriatic arthritis

The value of correctly diagnosing axial spondyloarthritis for patients and society

Semin Arthritis RheumPublished Cost-effectiveness modelling study

Authors' conclusion

Correct diagnosis of axSpA results in substantial health and cost benefits for patients and society. Not requiring IBP as mandatory for diagnosis of axSpA (algorithm M2) provides more value and would be preferable.

Study context

Population
Patients with low back pain referred to a rheumatologist (model using data from SPACE and other cohorts)
Comparison
Diagnostic algorithms for axSpA: Berlin vs Modification 1 vs Modification 2, and perfect diagnosis
Outcome
Health (QALYs) and costs (healthcare consumption and work productivity losses) per patient
Follow-up
60-year horizon
Methodological detailsdecision-tree combined with state-transition model, 60-year horizon, societal perspective
  • Decision-tree combined with state-transition model
  • 60-year horizon
  • Societal perspective

Main finding

As reported in the abstract

GroupValueCosts
M224.23 QALYs€157,469
BER23.96 QALYs€159,423
M124.15 QALYs€158,417

Value

M224.23 QALYs
BER23.96 QALYs
M124.15 QALYs

Costs

M2€157,469
BER€159,423
M1€158,417
Per correctly diagnosed axSpA patient, QALYs gained (societal perspective)
up to 4.7
Per correctly diagnosed axSpA patient, costs saved (societal perspective)
€60,000

Further findings

Hypothetical improvements in M2 sensitivity vs specificity

Improvements in M2 sensitivity gave slightly more value than improvements in specificity

Value of perfect diagnosis

Perfect diagnosis can cost this much per patient and still provide enough value
€7,500

Original publication

The value of correctly diagnosing axial spondyloarthritis for patients and society. Semin Arthritis Rheum. Published 5 July 2023. doi:10.1016/j.semarthrit.2023.152242

Composed by AI from the published abstract and checked against it. How Briefs are made →

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