Spondyloarthritis & psoriatic arthritis
Postpartum Depression in Reproductive-Age Women With and Without Rheumatic Disease: A Population-Based Matched Cohort Study
Main finding · Incident PPDResult — go to the resultAdjusted hazard ratio 1.22 95% CI 1.09–1.36Authors' conclusion
Postpartum depression is significantly higher in women of reproductive age with axSpA/PsA/RA when compared to those without RD.
Study context
- Population
- Pregnant women ≤ 55 years, 2013–2018 IBM MarketScan Commercial Claims and Encounters Database, continuous enrollment ≥ 6 months before last menstrual period and throughout pregnancy
- Participants
- 2,667 vs 10,668
- Exposure
- Women with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA) or rheumatoid arthritis (RA) vs matched women without rheumatic disease
- axSpA/PsA/RAn = 2,667
- Matched non-RD comparisonn = 10,668reference
- Outcome
- Incident postpartum depression
- Follow-up
- Within 1 year
Methodological detailspopulation-based, matched (1:4) on maternal age at delivery, prior history of depression and duration of depression before delivery, Cox frailty proportional hazards models
- Population-based
- Matched (1:4) on maternal age at delivery, prior history of depression and duration of depression before delivery
- Cox frailty proportional hazards models
Main finding
Incident PPD
Adjusted hazard ratio
1.22
95% CI 1.09–1.36
By group
axSpA/PsA/RAvs Matched non-RD comparison
aHR 1.22 (95% CI 1.09–1.36)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Follow-up time
Original publication
Postpartum Depression in Reproductive-Age Women With and Without Rheumatic Disease: A Population-Based Matched Cohort Study. J Rheumatol. Published 1 July 2023. doi:10.
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