Pediatric rheumatology

The risk of cardiovascular comorbidity in children with Behçet’s disease

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

Paediatric BD patients with vascular involvement may tend to have more cardiovascular risk factors.

Study context

Population
Paediatric patients with Behçet's disease (BD) (2015 Peadiatric BD (PEDBD) criteria), without active disease or other known cardiovascular risk factors16 female, 51.6%
Participants
31 patients
Exposure
Paediatric BD with vs without vascular involvement
Outcome
Abnormal ABPM

Main finding

As reported in the abstract

BD patients

34.4%

10 events

Observational data: associations, not effects.

Further findings

Carotid intima-media thickness (cIMT), mean arterial pressure, systolic and diastolic BP by ambulatory blood pressure monitoring (ABPM); abnormal ABPM, non-dipping, ambulatory hypertension

Similar between patients with and without vascular involvement

Echocardiography: left ventricle outflow tract velocity and velocity time integral

Significantly higher in BD patients with vascular involvement, which may indicate increased stiffness of the aorta

Original publication

The risk of cardiovascular comorbidity in children with Behçet’s disease. Rheumatology (Oxford). Published 3 October 2023. doi:10.1093/rheumatology/kead505

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