The rational use of glucocorticoids may reduce the risk of readmission in menopausal women with knee osteoarthritis: results from a five-year longitudinal study
Main finding · Early readmissionResult — go to the resultHazard ratio 0.04 95% CI 0.006 ≈0.284Authors' conclusion
GC use reduced the risk of readmission in menopausal women with knee OA, although this effect diminished over time.
Study context
- Population
- Menopausal women with knee osteoarthritis (OA) treated at a tertiary hospital affiliated with Shanxi Medical University, followed up September 2018–September 2023
- Participants
- 80 women
- Exposure
- GC use vs no GC use
- Outcome
- Risk of readmission
Methodological detailsfive-year follow-up, semi-variable coefficient shared Gamma frailty model (VCSGF), single tertiary hospital
- Five-year follow-up
- Semi-variable coefficient shared Gamma frailty model (VCSGF)
- Single tertiary hospital
Main finding
Early readmission
Hazard ratio
0.04
95% CI 0.006 ≈0.284
GCsvs No GCs
HR 0.04 (95% CI 0.006 ≈0.284)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Fold higher risk (95% CI) |
|---|---|
| Hospital admission with recurrent symptoms, by alcohol drinkingPatients who drink alcohol vs patients who do not · roughly | 3.35 (1.661~6.794) |
Original publication
The rational use of glucocorticoids may reduce the risk of readmission in menopausal women with knee osteoarthritis: results from a five-year longitudinal study. Arthritis Res Ther. Published 6 February 2025. doi:10. 1186/ s13075-025-03495-x
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