Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trial
Primary result · Hip pain severity (NRS 0-10), mean improvementResult — go to the resultMean difference 0.3 95% CI −0.3 to 0.8Authors' conclusion
Despite improvement in pain and function in both groups, adding moderate-intensity aerobic physical activity to resistance exercise did not lead to superior outcomes.
Study context
- Population
- People with a clinical diagnosis of symptomatic hip OA, Melbourne, Australia134 [68%] women, 62 [32%] men
- Participants
- 196 people
- Comparison
- Aerobic physical activity plus resistance exercise vs resistance exercise only
- AEROBIC + RESISTANCEn = 97
- RESISTANCE ONLYn = 99reference
- Primary endpoint
- Co-primary: change in hip pain severity (NRS 0-10, higher worse) and function (WOMAC 0-68, higher worse)
- Follow-up
- 3 months
Methodological detailscomparative effectiveness, web-based randomisation (1:1), People with lived experience of hip OA involved in study design
- Comparative effectiveness
- Web-based randomisation (1:1)
- People with lived experience of hip OA involved in study design
Primary result
Hip pain severity (NRS 0-10), mean improvement
Mean difference
0.3
95% CI −0.3 to 0.8
P = 0.36
Change by group
Aerobic + resistance
2.4
mean · SD 1.9
Resistance only
2.2
mean · SD 2.1
Aerobic + resistancevs Resistance only
mean difference 0.3 (95% CI −0.3 to 0.8); P = 0.36
As reported in the abstract
Further findings
Mean
| Outcome | AEROBIC + RESISTANCE | RESISTANCE ONLY | Mean difference (95% CI) | P value | |
|---|---|---|---|---|---|
| Co-primary: function (WOMAC 0-68), mean improvement · 3 monthsIntention-to-treat | 7.0 (SD 10.4) | 8.9 (SD 10.8) | −0.9 (−3.6 to 1.8) | P = 0.51 | |
| −4−202Difference (linear scale) |
Safety
Events
| Outcome | AEROBIC + RESISTANCE | RESISTANCE ONLY |
|---|---|---|
| Related adverse eventsNone of which were serious | 24 | 31 |
Original publication
Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trial. Lancet Rheumatol. Published 5 February 2025. doi:10.
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