Vasculitis & polymyalgia rheumatica
The provisional OMERACT ultrasonography score for giant cell arteritis
Authors' conclusion
We developed a provisional OGUS for potential use in clinical trials.
Study context
- Population
- Patients with new giant cell arteritis (GCA) (prospective cohort); reliability images from 16 patients with GCA and 7 controls; OMERACT ultrasonography LVV working group membersprospective cohort
- Participants
- 52 patients
- Outcome
- Metric properties of the OMERACT GCA Ultrasonography Score (OGUS)
Methodological detailsOMERACT Instrument Selection Algorithm, Delphi consensus (seven rounds), online reliability exercise, prospective cohort, intima-media thickness (IMT) measured at weeks 1, 3, 6, 12 and 24, 49 working group members invited to seven Delphi rounds; 35 conducted the reliability exercise
- OMERACT Instrument Selection Algorithm
- Delphi consensus (seven rounds)
- Online reliability exercise
- Prospective cohort
- IMT measured at weeks 1, 3, 6, 12 and 24
- 49 working group members invited to seven Delphi rounds; 35 conducted the reliability exercise
Performance
As reported in the abstract
- Delphi agreement on OMERACT GCA Ultrasonography Score (OGUS)
- 92.7%
- Interrater intraclass correlation coefficient (ICC) for OGUS
- 0.72-0.84
- Median intrareader ICC
- 0.91
- Sensitivity to change, baseline to each follow-up up to week 24 (SMD; large to very large)
- −1.19 to −2.16
- Correlation with ESR, CRP and BVAS (moderate)
- 0.37-0.48
Original publication
The provisional OMERACT ultrasonography score for giant cell arteritis. Ann Rheum Dis. Published 12 December 2022. doi:10. 1136/ ard-2022-223367
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