Vasculitis & polymyalgia rheumatica
Definitions and online reliability assessment of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group
Authors' conclusion
This OMERACT initiative established consensus-based definitions for US lesions in TAK and identified key relevant arterial segments, providing a reliable basis for the development of a standardized US composite score.
Study context
- Population
- Members of the OMERACT Ultrasound Working Group; Ultrasonography (US) images from TAK patients and healthy controls45 experts completed reliability exercise
- Outcome
- Consensus definitions and reliability of US lesions in TAK
Methodological detailsDelphi survey, web-based reliability exercise, two scoring rounds
- Delphi survey
- Web-based reliability exercise
- Two scoring rounds
Recommendations
As reported in the abstract
- Delphi rounds completed (47, 46 and 43 experts)
- 3
- Consensus lesions: 'macaroni sign', stenosis, occlusion
- 3
- Consensus arterial segments: bilateral common carotid, subclavian, axillary arteries, abdominal aorta
- 7
- Inter-rater reliability, moderate to good (Fleiss' κ)
- κ = 0.47-0.64
- Inter-rater reliability, 'macaroni sign' in carotid artery (highest)
- κ = 0.73
- Intra-rater reliability, good (Cohen's κ)
- κ = 0.72-0.79
Original publication
Definitions and online reliability assessment of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group. Semin Arthritis Rheum. Published 25 January 2026. doi:10. 1016/ j. semarthrit. 2026. 152927
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