Vasculitis & polymyalgia rheumatica

Definitions and online reliability assessment of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group

Semin Arthritis RheumPublished Delphi consensus and reliability study

Authors' conclusion

This OMERACT initiative established consensus-based definitions for US lesions in TAK and identified key relevant arterial segments, providing a reliable basis for the development of a standardized US composite score.

Study context

Population
Members of the OMERACT Ultrasound Working Group; Ultrasonography (US) images from TAK patients and healthy controls45 experts completed reliability exercise
Outcome
Consensus definitions and reliability of US lesions in TAK
Methodological detailsDelphi survey, web-based reliability exercise, two scoring rounds
  • Delphi survey
  • Web-based reliability exercise
  • Two scoring rounds

Recommendations

As reported in the abstract

Delphi rounds completed (47, 46 and 43 experts)
3
Consensus lesions: 'macaroni sign', stenosis, occlusion
3
Consensus arterial segments: bilateral common carotid, subclavian, axillary arteries, abdominal aorta
7
Inter-rater reliability, moderate to good (Fleiss' κ)
κ = 0.47-0.64
Inter-rater reliability, 'macaroni sign' in carotid artery (highest)
κ = 0.73
Intra-rater reliability, good (Cohen's κ)
κ = 0.72-0.79

Original publication

Definitions and online reliability assessment of elementary ultrasound lesions in Takayasu arteritis: a study from the OMERACT Ultrasound Working Group. Semin Arthritis Rheum. Published 25 January 2026. doi:10.1016/j.semarthrit.2026.152927

Composed by AI from the published abstract and checked against it. How Briefs are made →

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