Osteoarthritis

The prevalence of varus thrust: A systematic review and meta-analysis

Osteoarthritis CartilagePublished Systematic review and meta-analysis

Authors' conclusion

Varus thrust is prevalent in clinically studied knee OA cohorts, particularly in people with varus alignment and more severe radiographic OA.

Study context

Population
Adults with and without knee osteoarthritis (OA); varus thrust during gait assessed by clinical observation16 studies
Outcome
Prevalence of varus thrust
Methodological detailsPRISMA guidelines, two independent reviewers, Five electronic databases and Google Scholar searched from inception to January 21, 2025
  • PRISMA guidelines
  • Two independent reviewers
  • Five electronic databases and Google Scholar searched from inception to January 21, 2025

Pooled result

As reported in the abstract

Prevalence of varus thrust in knee OA

Knees with knee OA

20.6%

95% CI 15.4%–27.0%

Individuals with knee OA

26.9%

95% CI 21.6%–32.9%

Further pooled results

Varus thrust prevalence in knee OA with varus alignment (subgroup)

Varus alignment
34.9% (95% CI 27.6%-43.0%)

Varus thrust prevalence by radiographic OA severity (subgroup)

Increased with greater radiographic OA severity; K/L grade 4
54.3%

Varus thrust prevalence by sex (subgroup)

Numerically higher in males than females; between-subgroup difference not statistically significant

Original publication

The prevalence of varus thrust: A systematic review and meta-analysis. Osteoarthritis Cartilage. Published 8 May 2026. doi:10.1016/j.joca.2026.05.001

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