Systemic sclerosis & Raynaud's
The presence of abnormal septal motion on echocardiography is a predictor of abnormal cardiac magnetic resonance in systemic sclerosis
Authors' conclusion
This study indicates that the presence of ASM on ECHO is a predictor of abnormal CMR in SSc patients
Study context
- Population
- Patients with systemic sclerosis (SSc) seen at an outpatient referral centre, all assessed with ECG, Doppler ECHO and cardiac MRI (CMR)52% diffuse SSc
- Participants
- 93 patients
- Exposure
- Abnormal septal motion (ASM) on ECHO vs no ASM, as predictor of abnormal CMR
- Outcome
- Abnormal CMR findings with ASM on ECHO (age- and sex-adjusted)
Methodological detailssingle referral centre, age- and sex-adjusted model
- Single referral centre
- Age- and sex-adjusted model
Main finding
As reported in the abstract
- Increased extracellular volume, OR
- 4.43 (1.73, 11.38) (95% CI)
- Increased T1 relaxation time, OR
- 2.67 (1.09, 6.54) (95% CI)
- Increased T2 relaxation time, OR
- 2.56 (1.05, 6.22) (95% CI)
- Increased signal intensity ratio in T2-weighted imaging, OR
- 2.56 (1.05, 6.22) (95% CI)
- Late gadolinium enhancement, OR
- 3.85 (1.52, 9.76) (95% CI)
- Mid-wall fibrosis, OR
- 3.64 (1.48, 8.96) (95% CI)
Observational data: associations, not effects.
Further findings
Baseline ECG, ECHO and CMR findings
- Sinus rhythm
- 84 (90%)
- Left anterior fascicular block (most common ECG finding)
- 26 (28%)
- ASM on ECHO
- 43 (46%)
- Myocardial involvement (inflammation or fibrosis) on multiparametric CMR
- >50%
Original publication
The presence of abnormal septal motion on echocardiography is a predictor of abnormal cardiac magnetic resonance in systemic sclerosis. Rheumatology (Oxford). Published 22 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →