Gout & crystal arthritis

The OMERACT core domain sets for calcium pyrophosphate deposition disease

Semin Arthritis RheumPublished Consensus study

Methodological detailsOMERACT core domain set development, scoping review, qualitative study, Delphi surveys, ranking exercises, virtual e-module endorsement vote
  • OMERACT core domain set development
  • Scoping review
  • Qualitative study
  • Delphi surveys
  • Ranking exercises
  • Virtual e-module endorsement vote

Recommendations

As issued by the authors

  1. Chronic and recurrent CPPD core domains: pain intensity, joint tenderness, joint swelling, acute CPP crystal arthritis flares, overall function, patient global assessment of disease activity, physician global assessment of disease activity, and adverse events including death. Endorsed by 14/14 (100%) patient research partners and 85/87 (98%) other participants.

  2. Acute CPP crystal arthritis core domains: pain intensity, joint tenderness, joint swelling, duration of acute CPP crystal arthritis flare, overall function, patient global assessment of disease activity, and adverse events including death. Endorsed by 14/14 (100%) patient research partners and 83/86 (97%) other participants.

  3. Definitions for all core domains have been developed.

Original publication

The OMERACT core domain sets for calcium pyrophosphate deposition disease. Semin Arthritis Rheum. Published 3 June 2026. doi:10.1016/j.semarthrit.2026.153014

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