Gout & crystal arthritis

Core domain set for chronic and/or recurrent manifestations of calcium pyrophosphate deposition disease: OMERACT delphi survey to establish consensus

Semin Arthritis RheumPublished Delphi consensus survey

Authors' conclusion

This work has identified potential domains for the OMERACT core domain set for chronic and/or recurrent manifestations of CPPD disease. There was strong support for joint pain, joint tenderness, joint swelling, acute CPP crystal arthritis flare, overall function, and global assessments of disease activity as core domains.

Study context

Population
Patient research partners and other participants (mainly clinicians and researchers) for the OMERACT core domain set for chronic and/or recurrent CPPD disease
Comparison
Patient research partners (PRPs) vs Other
Outcome
Consensus: ≥70% of both patients and other participants scoring the domain as 'critically important domain to include'
Methodological detailsthree rounds, subsequent ranking exercise
  • Three rounds
  • Subsequent ranking exercise

Recommendations

As reported in the abstract

Domains reaching consensus as critically important
Domains reaching consensus as critically important
15

Further findings

Ranking exercise

Most highly ranked: joint pain, joint tenderness, joint swelling, acute CPP crystal arthritis flare and overall function

Original publication

Core domain set for chronic and/or recurrent manifestations of calcium pyrophosphate deposition disease: OMERACT delphi survey to establish consensus. Semin Arthritis Rheum. Published 7 March 2025. doi:10.1016/j.semarthrit.2025.152669

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