Lupus & antiphospholipid syndrome
The impact of Libman-sacks endocarditis on inpatient outcomes with systemic lupus erythematosus: A retrospective study
Main finding · Inpatient mortalityResult — go to the resultAdjusted odds ratio 9.74 CI 1.12–84.79Authors' conclusion
Patients who develop LSE were found to have significantly higher risks of inpatient mortality and cerebrovascular accidents.
Study context
- Population
- Adult patients hospitalised with Systemic Lupus Erythematosus (SLE), 2019–2020, National Inpatient Sample
- Participants
- 150,411 patients
- Exposure
- SLE with Libman-Sacks Endocarditis (LSE) vs SLE without LSE
- SLE with LSEn = 349
- Outcome
- Inpatient mortality
Methodological detailsNational Inpatient Sample database
- National Inpatient Sample database
Main finding
As reported in the abstract
Adjusted odds ratio
9.74
CI 1.12–84.79
p 0.04
SLE with LSEvs SLE without LSE
aOR 9.74 (CI 1.12–84.79); p 0.04
Observational data: associations, not effects.
Further findings
| Outcome | aOR (CI) | P value | |
|---|---|---|---|
| Acute HF | 1.18 (0.13–11.07) | p 0.88 | |
| AF | 4.45 (0.77–25.57) | p 0.10 | |
| Cerebrovascular accidents | 141.43 (16.59–1205.52) | P < 0.01 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Original publication
The impact of Libman-sacks endocarditis on inpatient outcomes with systemic lupus erythematosus: A retrospective study. Lupus. Published 2 April 2024. doi:10.
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