Lupus & antiphospholipid syndrome
The impact of a peer-mentoring intervention on self-reported flare and disease activity among African American women with Systemic Lupus Erythematosus (SLE)
Study context
- Population
- Adult African American women with SLE
- Comparison
- Peer-mentoring intervention vs social support control; peer mentors also assessed
- Primary endpoint
- Self-reported disease activity, symptom severity and flare frequency (Systemic Lupus Activity Questionnaire (SLAQ))
- Follow-up
- Baseline, 3, 6 and 12 months after the intervention
Methodological detailssub-analysis, linear and cumulative logit mixed models, adjusted for sociodemographic covariates
- Sub-analysis
- Linear and cumulative logit mixed models
- Adjusted for sociodemographic covariates
Primary result
As reported in the abstract
Symptom severity (SLAQ), Intervention
- Intervention reported sustained reductions in symptom severity over time, not statistically significant
Further findings
| Outcome | Mean difference (95% CI) | |
|---|---|---|
| Symptom severity (SLAQ), Mentors · 3 monthsMentorsvs Social support controlSignificant improvement | −2.53 (−4.95 to −0.11) | |
| −6−4−202Difference (linear scale) |
Employment and insurance status
- Employment and insurance status consistently associated with lower symptom burden and disease activity
Original publication
The impact of a peer-mentoring intervention on self-reported flare and disease activity among African American women with Systemic Lupus Erythematosus (SLE). Lupus. Published 11 February 2026. doi:10. 1177/ 09612033261422819
Composed by AI from the published abstract and checked against it. How Briefs are made →