Vasculitis & polymyalgia rheumatica
The epidemiology of pathologically confirmed clinically isolated aortitis: a North American population-based study
Authors' conclusion
CIA predominantly affects women in their eighth decade and is quite rare.
Study context
- Population
- Residents of Olmsted County, Minnesota screened for thoracic aortic aneurysm procedures, 2000–2021
- Participants
- 8 incident cases
- Outcome
- Incidence of pathologically confirmed CIA
Methodological detailsRochester Epidemiology Project, manual medical record review, age and sex adjusted to 2020 US total population
- Rochester Epidemiology Project
- Manual medical record review
- Age and sex adjusted to 2020 US total population
Main finding
As reported in the abstract
Age and sex adjusted annual incidence rate of CIA, per 1,000,000 individuals over age 50 years
Clinically isolated aortitis (CIA)
8.9
95% CI 2.7–15.1 · per 1,000,000 individuals over age 50 years
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Female sex | CIA 75% |
| Age at diagnosisAll diagnosed following ascending aortic aneurysm repair | CIA median 78.3 (IQR 70.2–78.9) years |
Duration of follow-up
- Median (IQR) duration of follow-up, years
- 8.7 (1.2-12.0)
Overall mortality vs age and sex matched general population
- Standardised mortality ratio (95% CI 0.51-3.68); did not differ
- 1.58
Original publication
The epidemiology of pathologically confirmed clinically isolated aortitis: a North American population-based study. Clin Exp Rheumatol. Published 16 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →