Vasculitis & polymyalgia rheumatica
Clinico-radiological correlation and prognostic value of baseline chest computed tomography in eosinophilic granulomatosis with polyangiitis
Authors' conclusion
Chest HRCT at diagnosis of EGPA may have prognostic value and help clinicians better manage these patients.
Study context
- Population
- Eosinophilic granulomatosis with polyangiitis (EGPA) patients with available chest high-resolution CT (HRCT) before any systemic treatment, three French hospitals
- Participants
- 46 patients
- Exposure
- HRCT pattern clusters: ground-glass vs bronchial vs extra-pulmonary pattern
- Outcome
- Prognostic value of baseline HRCT (HRCT characteristics correlated with clinical features and outcome)
Methodological detailsmulticentre, observational, three French hospitals, radiologists blinded to clinical data, semi-quantitative scoring
- Multicentre
- Observational
- Three French hospitals
- Radiologists blinded to clinical data
- Semi-quantitative scoring
Main finding
As reported in the abstract
baseline
- Abnormal parenchymal findings on HRCT
- 38 (82.6%)
- Bronchial wall thickening
- 69.6%
- Mosaic perfusion
- 63.0%
- Ground-glass opacities
- 32.6%
- Bronchiectasis
- 30.4%
- Mucous plugging
- 21.7%
- Consolidations
- 17.4%
Observational data: associations, not effects.
Further findings
Cardiac involvement
Positive ANCA
Steroid-dependency
Requirement for mepolizumab
Remission
Eosinophil count
Original publication
Clinico-radiological correlation and prognostic value of baseline chest computed tomography in eosinophilic granulomatosis with polyangiitis. Rheumatology (Oxford). Published 15 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →