Lupus & antiphospholipid syndrome
The cost of flares among patients with systemic lupus erythematosus with and without lupus nephritis in the United States
Authors' conclusion
Patients with SLE with LN have greater healthcare costs than those without LN. Flares among patients with LN were more frequent, severe, and costly than among patients without LN.
Study context
- Population
- Adults with systemic lupus erythematosus (SLE) identified 1 January 2016 to 31 December 2018 in a US claims database12,190 flares
- Participants
- 11,663 adults
- Exposure
- SLE with LN vs SLE without LN
- LNn = 2,916
- non-LNn = 8,747reference
- Outcome
- Healthcare costs (2019 US dollars) associated with SLE flares
- Follow-up
- 12 months following index
Methodological detailsmedical and pharmacy claims data (Optum Clinformatics)
- Medical and pharmacy claims data (Optum Clinformatics)
Main finding
As reported in the abstract
Total healthcare costs associated with SLE flares of any severity · 12 months follow-up
Observational data: associations, not effects.
Further findings
Cost per mild flare
Cost per moderate flare
Cost per severe flare
Proportion of flares that were moderate
Proportion of flares that were severe
| Outcome | LN | non-LN |
|---|---|---|
| Number of flares · follow-up period | 3494 events | 8696 events |
| Moderate flares per patientMean | 1.8 (SD 1.2) | 1.4 (SD 1.2) |
| Severe flares per patientMean | 0.2 (SD 0.6) | 0.1 (SD 0.3) |
Original publication
The cost of flares among patients with systemic lupus erythematosus with and without lupus nephritis in the United States. Lupus. Published 21 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →