Spondyloarthritis & psoriatic arthritis
The association of cervical and lumbar mobility with functional ability in axial spondyloarthritis: Insights from the CASTRO registry using Inertial Measurement Unit system
Authors' conclusion
This study suggests that cervical mobility is more strongly associated with functional ability than lumbar mobility in axSpA patients. However, the impact of cervical and lumbar mobility on functional ability varies with disease duration.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) from the Córdoba axSpA Task Force Registry and Outcomes (CASTRO) registry
- Participants
- 156 patients
- Exposure
- Non-longstanding vs longstanding disease duration
- Outcome
- Variability of BASFI explained by each spinal movement (R²), spinal mobility assessed with inertial measurement unit (IMU) sensor system
Methodological detailsregistry-based, univariable and multivariable linear regression
- Registry-based
- Univariable and multivariable linear regression
Main finding
As reported in the abstract
BASFI variability explained by spinal mobility (multivariable linear regression)
Cervical movements collectively, Bath Ankylosing Spondylitis Functional Index (BASFI) variability explained (R2 = 0.199)
19.9 %
Lumbar mobility, BASFI variability explained
11.3 %
Observational data: associations, not effects.
Further findings
| Outcome | Estimate |
|---|---|
| Association with BASFI in longstanding axSpA (subgroup)Longstanding · independently associated | B (cervical rotation) −0.68 (95 % CI 1.13 to −0.24) |
| Association with BASFI in longstanding axSpA (subgroup)Longstanding · independently associated | B (lumbar flexion) 0.65 (95 % CI 0.05–1.24) |
| Association with BASFI in non-longstanding axSpA (subgroup) | B (lumbar rotation) −0.51 (95 % CI 0.97 to −0.05) |
- Association with BASFI in non-longstanding axSpA (subgroup): lumbar mobility showed a stronger association with functional ability
Original publication
The association of cervical and lumbar mobility with functional ability in axial spondyloarthritis: Insights from the CASTRO registry using Inertial Measurement Unit system. Semin Arthritis Rheum. Published 6 March 2025. doi:10.
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