The association between myasthenia gravis and risk of fracture: a systematic review and meta-analysis
Pooled result · Risk of fractureResult — go to the resultOdds ratio 1.52 95% CI 0.74–3.12Authors' conclusion
In conclusion, we found no robust evidence to support the proposition that patients with MG are at higher risk for fracture than general comparators.
Study context
- Population
- Cohort studies comparing participants with and without myasthenia gravis (MG) for incidence of osteoporosis or fracture; databases searched from inception to end of November 2023
- Participants
- 34,865 participants3 studies
- Comparison
- MG vs non-MG
- Outcome
- Risk of fracture
Methodological detailsrandom effect model, Newcastle-Ottawa Scale quality assessment
- Random effect model
- Newcastle-Ottawa Scale quality assessment
Pooled result
As reported in the abstract
Odds ratio
1.52
95% CI 0.74–3.12
MGvs non-MG
OR 1.52 (95% CI 0.74–3.12)
Further pooled results
Risk of osteoporosis
- Quantitative analysis not performed due to limited studies
Original publication
The association between myasthenia gravis and risk of fracture: a systematic review and meta-analysis. Osteoporos Int. Published 15 May 2024. doi:10.
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