T-cell receptor repertoire and human leukocyte antigen (HLA) in osteoarthritis: A systematic literature review
Authors' conclusion
This analysis highlights the paucity of usable data in the literature
Study context
- Population
- Articles on T-Cell Receptor (TCR), major histocompatibility complex (MHC) and T-cell antigens in human and animal research in osteoarthritis (OA)of 405 screened records
- Participants
- 17 participants
- Outcome
- Topics of included articles (17 selected of 405 screened records; all human research)
Methodological detailsPRISMA 2020, PubMed and Embase, searched April 2024
- PRISMA 2020
- PubMed and Embase, searched April 2024
Main finding
As reported in the abstract
HLA as topic
65%
N=11
TCR repertoire as topic
41%
N=7
TCR articles: number of OA patients (mean ± SD)
4 ± 2
TCR articles using OA as a control disease
5 of 7
Original publication
T-cell receptor repertoire and HLA in osteoarthritis: A systematic literature review. Osteoarthritis Cartilage. Published 3 September 2025. doi:10. 1016/ j. joca. 2025. 08. 018
Composed by AI from the published abstract and checked against it. How Briefs are made →