Systemic sclerosis & Raynaud's

Systemic sclerosis-associated interstitial lung disease in the EUSTAR database: analysis by region

Rheumatology (Oxford)Published Retrospective cohort study

An erratum to this article was published (Rheumatology (Oxford), 1 Sep 2023 ↗)

Authors' conclusion

Our study highlights key differences among regions in terms of clinical presentation and prognosis of SSc-ILD.

Study context

Population
SSc patients in the EUSTAR database, clustered into seven geographical regions6,732 for survival analyses
Participants
9,260 patients
Exposure
SSc-ILD across seven predetermined geographical regions
Outcome
Prevalence, phenotype, treatment and prognosis of SSc-ILD by region
Methodological detailsEUSTAR database, seven predetermined geographical regions
  • EUSTAR database
  • Seven predetermined geographical regions

Main finding

As reported in the abstract

Prevalence of SSc-ILD
Prevalence of SSc-ILD in the overall population
50.2%

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
MMF prescribed at baseline in SSc-ILDAmerica (North and South) vs Asia and Oceania · across regionsAmerica (North and South) 31.6% · Middle East 31.7% · Asia and Oceania 4.3%P < 0.0001
Survival rate at end of follow-up (highest regions)America (North and South) 85.8% · Middle East 85.2%

Original publication

Systemic sclerosis-associated interstitial lung disease in the EUSTAR database: analysis by region. Rheumatology (Oxford). Published 12 October 2022. doi:10.1093/rheumatology/keac576

Composed by AI from the published abstract and checked against it. How Briefs are made →

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