Lupus & antiphospholipid syndrome
Systemic lupus erythematosus is a risk factor for having multiple subtypes of cutaneous lupus erythematosus
Authors' conclusion
Our study showed that almost one out of five CLE patients have multiple CLE subtypes, with SLE diagnosis being a significant risk factor.
Study context
- Population
- Patients with cutaneous lupus erythematosus (CLE) in the University of Texas Southwestern Cutaneous Lupus Registry, outpatient dermatology clinics, UT Southwestern and Parkland Health, 2009–2021
- Participants
- 319 patients
- Exposure
- Multiple CLE subtypes vs single CLE subtype
- Multiple CLE subtypesn = 59
- Outcome
- Frequency of and risk factors for having multiple CLE subtypes
Methodological detailsregistry-based, univariate and multivariable logistic regression
- Registry-based
- Univariate and multivariable logistic regression
Main finding
As reported in the abstract
Two or more CLE subtypes
Multiple CLE subtypes
18.5%
59
Observational data: associations, not effects.
Further findings
Univariate associations with multiple CLE subtypes
- Statistically significant differences in rates of systemic lupus erythematosus (SLE) diagnosis, history of positive ANA, arthritis, renal disorder and serositis
- Univariate analyses
Original publication
Systemic lupus erythematosus is a risk factor for having multiple subtypes of cutaneous lupus erythematosus. Lupus. Published 21 December 2024. doi:10.
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