Lupus & antiphospholipid syndrome

Association of truncal involvement in lupus erythematosus panniculitis patients with calcinosis cutis: A retrospective cohort study

LupusPublished Retrospective cohort study

Authors' conclusion

This cohort of LEP patients had over a third developing CC. LEP lesion location significantly differed in those who developed CC compared with those who did not.

Study context

Population
LEP patients from outpatient dermatology clinics at University of Texas Southwestern Medical Center and Parkland Health, January 2009 to December 2024
Participants
27 patients
Exposure
LEP patients with calcinosis cutis (CC) vs without CC
  • CCn = 10
  • No CCn = 17reference
Outcome
CC development based on clinical diagnosis from a dermatologist, biopsy, or radiographic imaging
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

CC in LEP · evaluation period

LEP patients with CC

10 of 27

37%

Observational data: associations, not effects.

Further findings

Truncal involvement of LEP lesions

P = 0.02

Head & neck involvement of LEP lesions

P = 0.04

Original publication

Association of truncal involvement in lupus erythematosus panniculitis patients with calcinosis cutis: A retrospective cohort study. Lupus. Published 8 June 2025. doi:10.1177/09612033251349451

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