Lupus & antiphospholipid syndrome
Subclinical atherosclerosis is associated with future cardiovascular events in lupus patients at apparent low cardiovascular risk
Main finding · CVEResult — go to the resultOdds ratio 17.2 95% CI 1.15–2499Authors' conclusion
Subclinical atherosclerosis defined as a carotid plaque >1.5 mm is significantly associated with the clinical cardiovascular risk in SLE.
Study context
- Population
- Consecutive SLE patients without known cardiovascular events (CVE) followed in a national reference center for rare diseases; CIMT assessed February 2012–February 201382.5% female
- Participants
- 63 patients
- Exposure
- Carotid plaque >1.5 mm at baseline vs no carotid plaque
- Carotid plaquen = 24
- Outcome
- CVE: MI, ischemic stroke or symptomatic peripheral arterial disease during follow-up
- Follow-up
- Median 10.7 [8.2-11.0] years
Methodological detailssingle evaluator, multivariable analysis
- Single evaluator
- Multivariable analysis
Main finding
CVE
Odds ratio
17.2
95% CI 1.15–2499
P = 0.039
Carotid plaquevs No carotid plaque
OR 17.2 (95% CI 1.15–2499); P = 0.039
As reported in the abstract
- CVE overall
- 7 (11.1%)
Observational data: associations, not effects.
Original publication
Subclinical atherosclerosis is associated with future cardiovascular events in lupus patients at apparent low cardiovascular risk. Lupus. Published 15 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →