Lupus & antiphospholipid syndrome

Spectrum of initial clinical presentations in Pakistani patients with systemic lupus erythematosus in the Arthritis Care Foundation lupus cohort

LupusPublished Retrospective descriptive study

Authors' conclusion

In our study, a majority of patients presented with mucocutaneous symptoms.

Study context

Population
Patients with systemic lupus erythematous (SLE) (ACR/EULAR 2019 criteria) registered with outdoor clinics of the Arthritis Care Foundation, Pakistan, Nov 2021–Mar 2023, with initial presentation documented at incident visit360 (92.8%) female
Participants
388 patients
Outcome
Pattern of initial clinical presentations of SLE
Methodological detailsmulticentre, electronic records review
  • Multicentre
  • Electronic records review

Main finding

As reported in the abstract

Initial clinical presentation

Mucocutaneous manifestations (most common)

336

86.7%

Musculoskeletal complaints

246

61.9%

Constitutional symptoms

78

20.1%

Renal involvement

42

10.8%

Observational data: associations, not effects.

Original publication

Spectrum of initial clinical presentations in Pakistani patients with systemic lupus erythematosus in the Arthritis Care Foundation lupus cohort. Lupus. Published 11 December 2023. doi:10.1177/09612033231221909

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