Lupus & antiphospholipid syndrome
Sociodemographic profiles and organ damage accural in the Black Women’s Experience Living with Lupus study
Authors' conclusion
Black/African American women with fewer socioeconomic resources and uncontrolled SLE are at greatest risk for increasing disease severity over time.
Study context
- Population
- Black/African American women with systemic lupus erythematosus (SLE) living in Atlanta, GA, enrolled in the BeWELL Study (May 2015 to April 2017)
- Participants
- 438 women
- Exposure
- Sociodemographic profiles vs Higher SES with Controlled SLE
- Outcome
- Timing and degree of new organ damage accrual
- Follow-up
- 2 years
Methodological detailslatent profile analysis, proportional hazard and Poisson regression models
- Latent profile analysis
- Proportional hazard and Poisson regression models
Main finding
As reported in the abstract
New organ damage (proportional hazard models)
Each group vs higher SES with Controlled SLEHazard ratio (95% CI)
Older/Lower SES with Uncontrolled SLE
2.41(1.39–4.19)
Younger/Lower SES with Uncontrolled SLE
1.56(0.92–2.67)
- Participants with new organ damage during follow-up
- ≈42%
Observational data: associations, not effects.
Further findings
| Outcome | B (95% CI) |
|---|---|
| Degree of organ damage accrual (Poisson regression) · 2 yearsOlder/Lower SES with Uncontrolled SLE vs Higher SES with Controlled SLE · SE = 0.24 | 0.98 (0.52–1.44) |
| Degree of organ damage accrual (Poisson regression) · 2 yearsYounger/Lower SES with Uncontrolled SLE vs Higher SES with Controlled SLE · SE = 0.23 | 0.72 (0.27–1.17) |
Original publication
Sociodemographic profiles and organ damage accural in the Black Women’s Experience Living with Lupus study. Lupus. Published 4 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →