Lupus & antiphospholipid syndrome
Sick leave and disability pension following delivery in women with systemic lupus erythematosus
Authors' conclusion
SLE mothers more often had work loss in the prenatal year to 3 years postpartum compared to non-SLE mothers. Lower education and sick leave in the year of delivery were associated with a higher odds of work loss in the first year postpartum in SLE.
Study context
- Population
- Mothers with and without systemic lupus erythematosus (SLE) with a singleton liveborn (2004–2008), Swedish Lupus Linkage cohortmatched cohort
- Participants
- 130 vs 440
- Exposure
- SLE mothers vs non-SLE mothers
- SLEn = 130
- Non-SLEn = 440reference
- Outcome
- Work loss (sum of sick leave and disability pension) from 1 year prenatally to 3 years postpartum
- Follow-up
- 1 year prenatally to 3 years postpartum
Methodological detailsmatched by age and month of delivery, Swedish Lupus Linkage cohort, adjusted logistic regression
- Matched by age and month of delivery
- Swedish Lupus Linkage cohort
- Adjusted logistic regression
Main finding
As reported in the abstract
Work loss in prenatal year, SLE vs non-SLE
42% vs 16%
Work loss at 3 years postpartum, SLE vs non-SLE
49% vs 15%
Observational data: associations, not effects.
Further findings
Factors associated with >30 days work loss in first year postpartum (SLE mothers)
| OR (95% CI) | ||
|---|---|---|
| > 30 days of sick leave in year of deliveryAdjusted logistic regression | 4.4 (1.5–12.9) | |
| ≤ 12 years of educationAdjusted logistic regression | 2.6 (1.1–6.0) | |
| 0.050.21520Odds ratio (log scale) |
Work loss days in SLE mothers
- Prenatal year, mean ± SD (days)
- 61 ± 112
- First year postpartum, mean ± SD (days)
- 38 ± 83
- Third year postpartum, mean ± SD (days)
- 71 ± 114
Factors associated with work loss in second year postpartum (SLE mothers)
- No covariates were associated
Original publication
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