Spondyloarthritis & psoriatic arthritis

Sexual function in axial spondyloarthritis: a systematic review and meta-analysis

Rheumatology (Oxford)Published Systematic review and meta-analysis

Authors' conclusion

Between one- to two-thirds of people with axSpA report a sexual dysfunction. Pooling of data from a small subset of studies demonstrated statistically, and at times clinically, poorer sexual function scores in both men and women compared with controls.

Study context

Population
Studies reporting sexual function outcomes in men or women with axial spondyloarthritis (axSpA); databases searched from inception to February 202537 studies
Comparison
People with axSpA vs controls
Outcome
Sexual function
Methodological detailsrandom-effects meta-analysis, narrative synthesis, quality assessed with modified ROBINS-E tool
  • Random-effects meta-analysis
  • Narrative synthesis
  • Quality assessed with modified ROBINS-E tool

Pooled result

As reported in the abstract

Sexual function in axSpA

General sexual dysfunction prevalence in axSpA (9 studies), ranging

32% to 71%

Original publication

Sexual function in axial spondyloarthritis: a systematic review and meta-analysis. Rheumatology (Oxford). Published 30 October 2025. doi:10.1093/rheumatology/keaf578

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