Sex Differences in Pain and Quantitative Sensory Testing in Patients With Rheumatoid Arthritis
Primary result · Pain intensity (NRS 0-10)Result — go to the resultAdjusted difference 0.83 95% CI 0.14–1.53Authors' conclusion
Women reported higher pain intensity and lower pressure pain detection thresholds (higher pain sensitivity) than men. However, pain interference, temporal summation, and conditioned pain modulation did not differ between men and women.
Study context
- Population
- Participants with rheumatoid arthritis (RA) in the Central Pain in Rheumatoid Arthritis cohort
- Comparison
- Women vs men with RA
- Primary endpoint
- Pain intensity (NRS 0-10)
Methodological detailsmultiple linear regression, adjusted for age, education, race, research site, depression, obesity, RA disease duration, swollen joint count, and CRP
- Multiple linear regression, adjusted for age, education, race, research site, depression, obesity, RA disease duration, swollen joint count, and CRP
Primary result
As reported in the abstract
Adjusted difference
0.83
95% CI 0.14–1.53
By group
Women
5.32
mean · SD 2.29
Men
4.60
mean · SD 2.23
Womenvs Men
adjusted difference 0.83 (95% CI 0.14–1.53)
Further findings
| Outcome | Estimate | |
|---|---|---|
| Pressure pain detection thresholdsWomenvs Men | adjusted difference (trapezius) −1.22 (95% CI −1.73 to −0.72) | |
| Pressure pain detection thresholdsWomenvs Men | adjusted difference (wrist) −0.57 (95% CI −1.07 to −0.06) | |
| Pressure pain detection thresholdsWomenvs Men | adjusted difference (knee) −1.10 (95% CI −2.00 to −0.21) | |
| −3−2−101Difference (linear scale) |
Pain interference (PROMIS), temporal summation, conditioned pain modulation
- No statistically significant differences between women and men
Original publication
Sex Differences in Pain and Quantitative Sensory Testing in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 3 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →