Rheumatoid arthritis

Are cleaning activities a source of exposure to crystalline silica in women with rheumatoid arthritis? A case–control study

RMD OpenPublished Case–control study

Authors' conclusion

Cleaning activities and dusty clothes laundry may be underestimated sources of SiO2 exposure in women with RA.

Study context

Population
Consecutive patients with rheumatoid arthritis (RA) not selected on professional activity, and matched controls from the French general population97 RA cases, 1:4 matched
Comparison
RA patients vs matched controls from the French general population
  • RAn = 97
Outcome
Main sources and levels of lifetime SiO2 exposure (Dust Exposure Life-Course Questionnaire (DELCQ) scores)
Methodological detailsage, gender and smoking status-matched controls (1:4)
  • Age, gender and smoking status-matched controls (1:4)

Main finding

As reported in the abstract

Source-specific SiO2 exposure in women
In women with RA, main SiO2 sources were cleaning activities and dusty clothes laundry, with higher exposure levels from these sources vs the general population
p<0.005

Further findings

Association of high SiO2 exposure with mediastinal lymphadenopathy in RA patients

OR (95% CI)
High SiO2 exposureIndependently associated6.3 (1.4–27.7)

Original publication

Are cleaning activities a source of exposure to crystalline silica in women with rheumatoid arthritis? A case–control study. RMD Open. Published 2 August 2023. doi:10.1136/rmdopen-2023-003205

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