Sex and country differences in gout: cross-country comparison between Sweden and the UK
Authors' conclusion
In the UK, gout was more frequently associated with modifiable risk factors. People with gout in Sweden were more commonly taking ULT and had lower frequency of gout flares and impact of gout.
Study context
- Population
- Primary care patients aged ≥18 years with gout in Sweden and the UK80% male (Sweden), 87% male (UK)
- Participants
- 784 vs 500
- Exposure
- Gout in Sweden vs the UK; females vs males
- Swedenn = 784
- UKn = 500reference
- Outcome
- Age at gout onset
Methodological detailscomparison of two separate primary care gout surveys, questionnaire
- Comparison of two separate primary care gout surveys
- Questionnaire
Main finding
As reported in the abstract
- Swedish patients significantly older at gout onset
- Sweden vs UK: P < 0.0001
Observational data: associations, not effects.
Further findings
Mean
| Outcome | Sweden | UK | P value |
|---|---|---|---|
| Number of gout flaresAge-adjusted | 1.6 (SD 3.6) | 2.2 (SD 1.7) | P = 0.003 |
| Age at gout onset by sex (pooled across countries)Females vs Males | P < 0.0001 |
- Use of uratelowering therapy (ULT) · age-adjusted
- P = 0.0005
- Age at gout onset by sex (pooled across countries): Females mean 67 (SD 13)
- Age at gout onset by sex (pooled across countries): Males mean 56 (SD 15)
Age at gout onset by sex (pooled across countries)
- Females more often obese, higher diuretic use, greater impact of gout, more pain and physical limitations; no sex differences in ULT or flares
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Sex and country differences in gout: cross-country comparison between Sweden and the UK. Scand J Rheumatol. Published 23 February 2023. doi:10.
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