Spondyloarthritis & psoriatic arthritis

Severe impairments in work ability among patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA): results from the RABBIT-SpA Register

RMD OpenPublished Cross-sectional study

Authors' conclusion

Around 25% of patients of working age with axSpA and PsA were non-employed and two-thirds of employed patients reported moderate/poor work ability.

Study context

Population
Patients aged 18–65 years with physician-confirmed axSpA or PsA in the RABBIT-SpA Registeranalysed
Participants
2,655 patients
Exposure
Employed with good/excellent Work Ability Index (WAI) vs employed with moderate/poor WAI vs non-employed
  • axSpAn = 1,366
  • PsAn = 1,276
Outcome
Work ability (Work Ability Index, 7-49 points, higher scores=better), categorised as good/excellent (≥37) or moderate/poor (≤36)
Methodological detailsdata from the prospective RABBIT-SpA cohort, descriptive analyses
  • Data from the prospective RABBIT-SpA cohort
  • Descriptive analyses

Main finding

As reported in the abstract

Values

Employed axSpA 80% · PsA 69%

Moderate/poor WAI axSpA 70%

Moderate/poor WAI among employed PsA 71%

Observational data: associations, not effects.

Further findings

Factors associated with non-employment or moderate/poor WAI (both cohorts)

Vs good/excellent WAI, non-employed or moderate/poor WAI more often female, older, obese, smokers and had fewer years of education
Lower inflammatory markers, fewer comorbidities and lower disease activity mainly in good/excellent WAI group; non-employed showed poorest clinical and patient-reported factors, followed by moderate/poor WAI

Original publication

Severe impairments in work ability among patients with axSpA and PsA: results from the RABBIT-SpA Register. RMD Open. Published 24 March 2026. doi:10.1136/rmdopen-2025-006338

Composed by AI from the published abstract and checked against it. How Briefs are made →

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