Serum glutathione peroxidase 1 levels associate with cardiometabolic comorbidity in rheumatoid arthritis
Authors' conclusion
High values of serum GPx1is linked to the cardiometabolic features that frequently accompany RA.
Study context
- Population
- Patients with rheumatoid arthritis (RA); evaluation of disease characteristics, lipid profile, insulin resistance, metabolic syndrome, SCORE2 CV risk and carotid US
- Participants
- 150 patients
- Outcome
- Association of serum GPx1 levels with disease characteristics in RA, with emphasis on CV comorbidity
Methodological detailsmultivariable linear regression
- Multivariable linear regression
Main finding
As reported in the abstract
Serum GPx1 associations (multivariable)
- No association with RA disease characteristics, incl. acute-phase reactants and disease activity indices
- Metabolic syndrome and atherogenic lipid profile linked to higher serum GPx1 after multivariable adjustment
- SCORE2 CV risk positively and significantly associated with elevated GPx1
Observational data: associations, not effects.
Original publication
Serum glutathione peroxidase 1 levels associate with cardiometabolic comorbidity in rheumatoid arthritis. Clin Exp Rheumatol. Published 15 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →