Spondyloarthritis & psoriatic arthritis

Sacroiliac joint involvement in psoriatic arthritis – MRI, radiographic and clinical findings in 581 European routine care patients

Arthritis Res TherPublished Cross-sectional study

Authors' conclusion

In this large European cohort, one-third of routine care PsA patients had axial involvement, based on global SIJ MRI assessment.

Study context

Population
Patients with a clinical diagnosis of PsA or of axSpA with psoriasis and available routine care sacroiliac joint (SIJ) MRIs, five European registries in the EuroSpA collaborationmean age 45 years, 47% male
Participants
581 patients
Outcome
Occurrence and characteristics of MRI and radiographic SIJ involvement
Methodological detailsmulticentre, five European registries (EuroSpA collaboration), central assessment of SIJ MRIs and radiographs
  • Multicentre
  • Five European registries (EuroSpA collaboration)
  • Central assessment of SIJ MRIs and radiographs

Main finding

As reported in the abstract

SpA-indicative SIJ-MRI findings (MRI-axPsA)

SpA-indicative SIJ-MRI findings (MRI-axPsA)

31%

In MRI-axPsA: Bone marrow edema (BME)

69%

In MRI-axPsA: erosions

68%

In MRI-axPsA: fat lesions

58%

Observational data: associations, not effects.

Further findings

Differential diagnoses on SIJ MRI

Osteitis condensans ilii
8%
Probable strain-related BME
11%
Degenerative disease
16%

Radiographic and MRI findings in patients with radiographs (n = 259)

Met radiographic mNY criteria for AS
29%
SpA-indicative MRI findings
38%

Factors associated with MRI-detected axial involvement

Male sex, HLA-B27 positivity, elevated CRP and history of inflammatory back pain (but not current back pain) independently associated

Original publication

Sacroiliac joint involvement in psoriatic arthritis – MRI, radiographic and clinical findings in 581 European routine care patients. Arthritis Res Ther. Published 29 September 2025. doi:10.1186/s13075-025-03652-2

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