Spondyloarthritis & psoriatic arthritis
Sacroiliac joint involvement in psoriatic arthritis – MRI, radiographic and clinical findings in 581 European routine care patients
Authors' conclusion
In this large European cohort, one-third of routine care PsA patients had axial involvement, based on global SIJ MRI assessment.
Study context
- Population
- Patients with a clinical diagnosis of PsA or of axSpA with psoriasis and available routine care sacroiliac joint (SIJ) MRIs, five European registries in the EuroSpA collaborationmean age 45 years, 47% male
- Participants
- 581 patients
- Outcome
- Occurrence and characteristics of MRI and radiographic SIJ involvement
Methodological detailsmulticentre, five European registries (EuroSpA collaboration), central assessment of SIJ MRIs and radiographs
- Multicentre
- Five European registries (EuroSpA collaboration)
- Central assessment of SIJ MRIs and radiographs
Main finding
As reported in the abstract
SpA-indicative SIJ-MRI findings (MRI-axPsA)
SpA-indicative SIJ-MRI findings (MRI-axPsA)
31%
In MRI-axPsA: Bone marrow edema (BME)
69%
In MRI-axPsA: erosions
68%
In MRI-axPsA: fat lesions
58%
Observational data: associations, not effects.
Further findings
Differential diagnoses on SIJ MRI
- Osteitis condensans ilii
- 8%
- Probable strain-related BME
- 11%
- Degenerative disease
- 16%
Radiographic and MRI findings in patients with radiographs (n = 259)
- Met radiographic mNY criteria for AS
- 29%
- SpA-indicative MRI findings
- 38%
Factors associated with MRI-detected axial involvement
- Male sex, HLA-B27 positivity, elevated CRP and history of inflammatory back pain (but not current back pain) independently associated
Original publication
Sacroiliac joint involvement in psoriatic arthritis – MRI, radiographic and clinical findings in 581 European routine care patients. Arthritis Res Ther. Published 29 September 2025. doi:10. 1186/ s13075-025-03652-2
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