Lupus & antiphospholipid syndrome

Rural–urban disparities in hospitalisation for myocardial infarction in systemic lupus erythematosus in the USA

Lupus Sci MedPublished Retrospective cross-sectional study

Main finding · MI hospitalisationResult — go to the resultAdjusted odds ratio 1.98 95% CI 1.71–2.29

Authors' conclusion

Rural residence doubled the risk of MI hospitalisation in people with SLE independent of demographics, payer status, social determinants of health and hospital characteristics.

Study context

Population
Hospitalisations of people with a diagnosis of SLE, US National Inpatient Sample 2016–2019
Exposure
Rural vs urban residence in people with SLE
Outcome
MI hospitalisation
Methodological detailsUS National Inpatient Sample 2016-2019, multivariable-adjusted
  • US National Inpatient Sample 2016-2019
  • Multivariable-adjusted

Main finding

As reported in the abstract

Adjusted odds ratio

1.98

95% CI 1.71–2.29

By group

Ruralvs Urban
aOR 1.98 (95% CI 1.71–2.29)

Observational data: associations, not effects.

Further findings

Other factors associated with myocardial infarction (MI) risk

Male sex, Medicaid or private insurance, urban not teaching or urban teaching hospital, Midwest region and private hospital control (for profit or not for profit) significantly associated with MI risk

Original publication

Rural–urban disparities in hospitalisation for myocardial infarction in systemic lupus erythematosus in the USA. Lupus Sci Med. Published 28 April 2025. doi:10.1136/lupus-2025-001516

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