Lupus & antiphospholipid syndrome
Prevalence of sarcopenia and its association with clinical features and health-related quality of life in Brazilian women with systemic lupus erythematosus
Authors' conclusion
In Brazilian patients with SLE with inactive or low disease activity, the prevalence of sarcopenia was low. However, low muscle strength, low muscle-specific strength and low physical performance were correlated with worse HRQoL
Study context
- Population
- Brazilian women with systemic lupus erythematosus (SLE) aged 18–50 years
- Participants
- 73 women
- Outcome
- Prevalence of sarcopenia (European Working Group on Sarcopenia in Older People-2 criteria)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Prevalence of sarcopenia
Probable sarcopenia
11.1%
Sarcopenia
2.7%
Observational data: associations, not effects.
Further findings
Muscle measures
- Handgrip strength, mean ±SD
- 25.58±8.31 kg
- ASMI, mean ±SD
- 6.62±0.97 kg/m²
- Muscle-specific strength, mean ±SD
- 6.6±2.3
- TUG, median (IQR)
- 6.9 (6.1-8.2) s
Association with health-related quality of life (HRQoL)
- Lower muscle strength, lower muscle-specific strength, lower physical performance and sarcopenia correlated with worse HRQoL
- P < 0.05
Original publication
Prevalence of sarcopenia and its association with clinical features and health-related quality of life in Brazilian women with systemic lupus erythematosus. Lupus Sci Med. Published 28 April 2025. doi:10.
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