Lupus & antiphospholipid syndrome
Relationship between sarcopenia and lifestyle in patients with systemic lupus erythematosus: A one-institution cross-sectional analysis
Authors' conclusion
This study suggests that dietary factors, such as monounsaturated fatty acids, brightly colored vegetables, meat, and grains, may be associated with sarcopenia in patients with SLE.
Study context
- Population
- Clinical immunology outpatients with systemic lupus erythematosus (SLE) at one medical facility (median age 49.5, 83% women)
- Participants
- 109 outpatients
- Exposure
- Sarcopenia vs no sarcopenia
- Sarcopenian = 10
- Outcome
- Associations of lifestyle factors (diet, physical activity) with sarcopenia
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Dietary factors associated with sarcopenia (logistic regression)
Sarcopenia
9.2%
10
- Higher monounsaturated fatty acids intake, OR
- 0.09 (95% CI 0.01-0.97)
- Higher brightly colored vegetables intake, OR
- 0.04 (95% CI 0.002-0.79)
- Higher meat intake, OR
- 0.10 (95% CI 0.01-0.95)
- Higher grains intake, OR
- 17.33 (95% CI 1.09-276.76)
Observational data: associations, not effects.
Further findings
Lifestyle differences, sarcopenia vs no sarcopenia
- Significantly lower n-6 fatty acids intake in sarcopenia (p = 0.009)
- Longer weekday sitting time in sarcopenia (p = 0.033)
Original publication
Relationship between sarcopenia and lifestyle in patients with systemic lupus erythematosus: A one-institution cross-sectional analysis. Lupus. Published 28 March 2026. doi:10. 1177/ 09612033261440580
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