Lupus & antiphospholipid syndrome

Relationship between sarcopenia and lifestyle in patients with systemic lupus erythematosus: A one-institution cross-sectional analysis

LupusPublished Cross-sectional study

Authors' conclusion

This study suggests that dietary factors, such as monounsaturated fatty acids, brightly colored vegetables, meat, and grains, may be associated with sarcopenia in patients with SLE.

Study context

Population
Clinical immunology outpatients with systemic lupus erythematosus (SLE) at one medical facility (median age 49.5, 83% women)
Participants
109 outpatients
Exposure
Sarcopenia vs no sarcopenia
  • Sarcopenian = 10
Outcome
Associations of lifestyle factors (diet, physical activity) with sarcopenia
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Dietary factors associated with sarcopenia (logistic regression)

Sarcopenia

9.2%

10

Higher monounsaturated fatty acids intake, OR
0.09 (95% CI 0.01-0.97)
Higher brightly colored vegetables intake, OR
0.04 (95% CI 0.002-0.79)
Higher meat intake, OR
0.10 (95% CI 0.01-0.95)
Higher grains intake, OR
17.33 (95% CI 1.09-276.76)

Observational data: associations, not effects.

Further findings

Lifestyle differences, sarcopenia vs no sarcopenia

Significantly lower n-6 fatty acids intake in sarcopenia (p = 0.009)
Longer weekday sitting time in sarcopenia (p = 0.033)

Original publication

Relationship between sarcopenia and lifestyle in patients with systemic lupus erythematosus: A one-institution cross-sectional analysis. Lupus. Published 28 March 2026. doi:10.1177/09612033261440580

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