Routine radiographs of hands and feet do not have diagnostic or prognostic value in patients with clinically suspect arthralgia: a large longitudinal study
Authors' conclusion
At CSA onset, radiographic erosive disease is rare. In addition, it is rarely progressive within the CSA phase and not predictive for IA development.
Study context
- Population
- Patients with clinically suspect arthralgia (CSA) of the Leiden CSA cohort, followed 2 years or until inflammatory arthritis1,497 radiographs
- Participants
- 749 patients
- Outcome
- Prevalence of radiographic erosive disease in CSA and its progression over time
- Follow-up
- 2-year follow-up
Methodological detailslongitudinal, stratified for ACPA status
- Longitudinal
- Stratified for ACPA status
Main finding
As reported in the abstract
Radiographic erosive disease at baseline
Median SHS-erosion score at baseline (IQR 0-1)
0
Rheumatoid arthritis (RA)-specific erosive disease according to the radiologist
1.7%
RA-specific erosive disease according to the American College of Rheumatology (ACR)/EULAR criteria
2.5%
Patients progressing ≥5 SHS-erosion points during follow-up
0
Observational data: associations, not effects.
Further findings
Inflammatory arthritis (IA) development by baseline erosive disease
| HR (95% CI) | ||
|---|---|---|
| Erosive disease at CSA onsetNot associated | 0.98 (0.40–2.44) | |
| 0.512Hazard ratio (log scale) |
Original publication
Routine radiographs of hands and feet do not have diagnostic or prognostic value in patients with clinically suspect arthralgia: a large longitudinal study. RMD Open. Published 12 November 2024. doi:10.
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