Spondyloarthritis & psoriatic arthritis
Role of Patrick-FABER test in detecting sacroiliitis and diagnosing spondyloarthritis in subjects with low back pain
Authors' conclusion
Our study shows that Patrick-FABER test positivity could represent a useful clinical test for addressing the use of sacroiliac joints MRI and SpA diagnosis in subjects with LBP.
Study context
- Population
- Subjects with low back pain (LBP) (61.8% male; median age 45 (21–69) years; LBP duration 78 (3–240) months)
- Participants
- 110 subjects
- Comparison
- Patrick-FABER test vs sacroiliac joint magnetic resonance imaging (MRI) for sacroiliitis
- Outcome
- Sensitivity, specificity and predictive value of Patrick-FABER test for MRI sacroiliitis and SpA diagnosis
Methodological detailsconsecutive enrolment, blinded assessors
- Consecutive enrolment
- Blinded assessors
Performance
As reported in the abstract
Diagnosis of MRI sacroiliitis
| Test or model | Sensitivity | Specificity | PPV | NPV | Overall diagnostic accuracy |
|---|---|---|---|---|---|
| Patrick-FABER test | 76.2% (95% CI: 60.5-87.9%) | 66.2% (95% CI: 53.6-77.2%) | 58.1% (95% CI: 44.1-71.3%) | 81.8% (95% CI: 69.1-90.9%) | 70% |
Patrick-FABER test
Sensitivity76.2% (95% CI: 60.5-87.9%)
Specificity66.2% (95% CI: 53.6-77.2%)
PPV58.1% (95% CI: 44.1-71.3%)
NPV81.8% (95% CI: 69.1-90.9%)
Overall diagnostic accuracy70%
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Odds of sacroiliitis by Patrick-FABER sign and smokingPositive Patrick-FABER signvs Negative sign | 6.3 (2.5–15.6) | ||
| Odds of sacroiliitis by Patrick-FABER sign and smokingSmokersvs Non-smokers | 2.7 (1.1–7) | P = 0.01 | |
| 0.050.21520Odds ratio (log scale) |
- Odds of sacroiliitis by Patrick-FABER sign and smoking: p for association of smoking status with sacroiliitis and spondyloarthritis (SpA) diagnosis
Odds of sacroiliitis by Patrick-FABER sign and smoking
- Patrick-FABER sign associated with MRI inflammatory sacroiliitis lesions and SpA diagnosis (univariate and multivariate analysis)
Original publication
Role of Patrick-FABER test in detecting sacroiliitis and diagnosing spondyloarthritis in subjects with low back pain. Clin Exp Rheumatol. Published 30 January 2023. doi:10.
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