Pediatric rheumatology

Blurring and Irregularity of the Subchondral Cortex in Pediatric Sacroiliac Joints on T1 Images: Incidence of Normal Findings That Can Mimic Erosions

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

At least two-thirds (65%) of normal pediatric SI joints showed at least 1 feature that is a component of the adult definition of SI joint erosions, risking overdiagnosis of sacroiliitis.

Study context

Population
Children (mean age 12.4 years, range 6.1–18.0) with sacroiliac (SI) joint magnetic resonance imaging (MRI) without sacroiliitis132 girls
Participants
251 children
Exposure
Nonrheumatic vs Low back pain
  • Nonrheumaticn = 127
  • Low back painn = 124
Outcome
Prevalence of subchondral bone variations mimicking erosions on T1-weighted MRI of pediatric SI joints (visibility, blurring, irregularity of cortical black line)
Methodological detailsblinded readers (3 radiologists), 2 cohorts
  • Blinded readers (3 radiologists)
  • 2 cohorts

Main finding

As reported in the abstract

Cortical black line features (agreement of ≥2 readers)
Cortical black line partially absent
88.4%
Cortical black line blurred
34.7%
Cortical black line irregular
41.4%
Clearly visualised, sharply delineated SI joints with none of these features (≥2 readers)
8.0%
Clearly visualised, sharply delineated SI joints with none of these features (all 3 readers agreeing)
35.1%

Observational data: associations, not effects.

Further findings

Location of features

All features most common on iliac side of SI joints and at first sacral vertebra level

Differences by sex, cohort and age

No significant difference between sexes or cohorts; findings similar across pediatric age groups

Original publication

Blurring and Irregularity of the Subchondral Cortex in Pediatric Sacroiliac Joints on T1 Images: Incidence of Normal Findings That Can Mimic Erosions. Arthritis Care Res (Hoboken). Published 2 September 2022. doi:10.1002/acr.24746

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