Lupus & antiphospholipid syndrome
Role of [68Ga]-pentixafor positron emission tomography/computed tomography imaging in assessing disease activity in patients with lupus nephritis: A pilot study
Authors' conclusion
68Ga-pentixafor PET is not a suitable imaging modality for assessment of disease activity in lupus nephritis patients.
Study context
- Population
- Patients with histopathologically confirmed LN referred for 68Ga-pentixafor PET/CT
- Participants
- 18 patients
- Outcome
- Renal uptake of 68Ga-pentixafor in LN
Methodological detailssingle-group imaging study
- Single-group imaging study
Main finding
As reported in the abstract
Renal 68Ga-pentixafor uptake vs histopathological class
- No significant association between mean renal SUVmax of bilateral kidneys and histopathological class
- No heterogeneity in uptake patterns attributable to the disease process
Original publication
Role of [68Ga]-pentixafor positron emission tomography/computed tomography imaging in assessing disease activity in patients with lupus nephritis: A pilot study. Lupus. Published 10 September 2023. doi:10. 1177/ 09612033231201625
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