Risk of Incident Heart Failure and Heart Failure Subtypes in Patients With Rheumatoid Arthritis
Main finding · Incident HFResult — go to the resultHazard ratio 1.79 95% CI 1.38–2.32Authors' conclusion
RA was associated with a higher rate of HF overall compared with non-RA, even after adjustment for established CVD risk factors.
Study context
- Population
- Participants consenting to broad research at two large academic centers (mean age 51.4 and 51.7 years; 78.7% female)matched cohort
- Participants
- 1,445 vs 4,335
- Exposure
- Rheumatoid arthritis (RA) vs matched non-RA comparators
- RAn = 1,445
- Non-RAn = 4,335reference
- Outcome
- Incident heart failure (HF) and HF subtypes (HF with preserved ejection fraction (HFpEF), HFrEF)
Methodological detailsmatched, two large academic centers, Cox proportional hazards models
- Matched
- Two large academic centers
- Cox proportional hazards models
Main finding
Incident HF
Hazard ratio
1.79
95% CI 1.38–2.32
RAvs Non-RA
HR 1.79 (95% CI 1.38–2.32)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| HFpEF | 1.99 (1.43–2.77) | |
| HFrEFNo statistical difference | 1.45 (0.81–2.60) | |
| 0.20.5125Hazard ratio (log scale) |
HFpEF as share of HF (most common subtype)
Original publication
Risk of Incident Heart Failure and Heart Failure Subtypes in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 16 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →