A simple heart failure detection score for rheumatology practice: findings from the Kyoto University Rheumatoid Arthritis Management Alliance (KURAMA) cohort
Authors' conclusion
HF affects over one in four RA outpatients.
Study context
- Population
- Outpatients with RA, KURAMA cohort
- Participants
- 542 outpatients
- Exposure
- Four-factor heart failure (HF) detection score vs NT-proBNP ≥ 125 pg/ml
- Outcome
- Prevalence of HF
Methodological detailsprespecified multistep HF algorithm, adaptive LASSO regression
- Prespecified multistep HF algorithm
- Adaptive LASSO regression
Main finding
As reported in the abstract
HF prevalence
HF detected in patients with RA
26.5%
Observational data: associations, not effects.
Further findings
| Outcome | Four-factor HF detection score | NT-proBNP ≥ 125 pg/ml |
|---|---|---|
| Discrimination for HF (AUC) | ||
| AUC | 0.793 | 0.814 |
Independent non-cardiac factors associated with HF
- Older age, lower haemoglobin (Hb), higher serum creatinine and higher Simplified Disease Activity Index (SDAI)
Discrimination for HF (AUC)
- Score AUC comparable to that of NT-proBNP ≥ 125 pg/ml alone
Original publication
A simple heart failure detection score for rheumatology practice: findings from the KURAMA cohort. Rheumatology (Oxford). Published 7 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →