Risk factors for refracture or new vertebral compression fractures after percutaneous vertebroplasty: a systematic review and meta-analysis
Study context
- Population
- Patients with osteoporotic vertebral compression fractures treated with percutaneous vertebroplasty; studies from July 2013 through May 2024
- Participants
- 3.821 patients9 studies
- Comparison
- Patients with a new fracture after percutaneous vertebroplasty vs patients without any fracture after vertebroplasty
- Outcome
- Risk factors for secondary fractures after percutaneous vertebroplasty (fracture vs non fracture group)
Methodological detailsNewcastle-Ottawa Scale quality assessment
- Newcastle-Ottawa Scale quality assessment
Pooled result
As reported in the abstract
Odds ratio (95% CI)P value
Smokingz = 3.32
1.62(1.22–2.15)
P = 0.001Type 2 diabetesz = 2.83
1.40(1.11–1.76)
P = 0.005- Overall secondary fracture incidence
- 16.6%
Further pooled results
Overall secondary fracture incidence · median follow-up 21 months
- Overall secondary fracture incidence
- 16.6%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Risk factors for refracture or new vertebral compression fractures after percutaneous vertebroplasty: a systematic review and meta-analysis. Osteoporos Int. Published 11 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →