A potential novel predictor of 1-year mortality in elderly hip fracture patients-albumin haemoglobin index
Authors' conclusion
AHI is a potential novel predictor of 1-year mortality in elderly hip fracture patients, with prognostic performance comparable to RAR and superior to RDW.
Study context
- Population
- Patients aged ≥ 65 years who underwent hip fracture surgery, January 2020 to December 2021, managed in a Fracture Liaison Service
- Participants
- 775 patients
- Exposure
- Preoperative albumin haemoglobin index (AHI) vs other preoperative blood parameters (RDW/albumin ratio (RAR), RDW) for predicting 1-year mortality
- Outcome
- 1-year mortality
- Follow-up
- 1 year
Methodological detailsROC analysis, Cox proportional hazards models
- ROC analysis
- Cox proportional hazards models
Main finding
As reported in the abstract
Prognostic performance for 1-year mortality (ROC)
| Group | AUC |
|---|---|
| AHI | 0.75 (95% CI 0.71-0.80), p < 0.001 |
| RAR | 0.77 (95% CI 0.73-0.82) |
| RDW | 0.72 (95% CI 0.67-0.77) |
AUC
AHI0.75 (95% CI 0.71-0.80), p < 0.001
RAR0.77 (95% CI 0.73-0.82)
RDW0.72 (95% CI 0.67-0.77)
- 1-year mortality rate
- 16.6% (129/775)
Observational data: associations, not effects.
Further findings
Association with 1-year mortality (Cox models)
| aHR (95% CI) | P value | ||
|---|---|---|---|
| AHICutoff AHI < 3331 | 3.67 (2.44–5.51) | P < 0.001 | |
| RARCutoff RAR > 0.468 | 3.94 (2.62–5.90) | ||
| RDWCutoff RDW > 14.15% | 2.12 (1.43–3.14) | ||
| 0.20.5125Adjusted hazard ratio (log scale) |
Mortality at 3 and 6 months (hazard models)
- Consistent trends at 3 and 6 months for AHI < 3331, RAR > 0.468 and RDW > 14.15%
Original publication
A potential novel predictor of 1-year mortality in elderly hip fracture patients-albumin haemoglobin index. Osteoporos Int. Published 10 June 2025. doi:10. 1007/ s00198-025-07566-2
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